Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
WG | Wegener granulomatosis | 0.595 | 0.808 | |||
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TNFSF13B | Q9Y275 | TNF superfamily member 13b | 0.98 | 0.460 | 0.731 | |
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TLR9 | Q9NR96 | toll like receptor 9 | 9.8E-06 | 0.411 | 0.885 | |
TLR4 | O00206 | toll like receptor 4 | 4.6E-09 | 0.321 | 0.962 | |
TIMP1 | P01033 | TIMP metallopeptidase inhibitor 1 | Enzyme modulator | 0.50 | 0.380 | 0.885 |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
RBM45 | Q8IUH3 | RNA binding motif protein 45 | 2.1E-10 | 0.383 | 0.846 | |
PTPN22 | Q9Y2R2 | protein tyrosine phosphatase non-receptor type 22 | 3.5E-21 | 0.438 | 0.846 | |
PDCD1 | Q15116 | programmed cell death 1 | 0.42 | 0.402 | 0.846 | |
MS4A1 | P11836 | membrane spanning 4-domains A1 | Receptor | 5.1E-05 | 0.411 | 0.846 |
MPO | P05164 | myeloperoxidase | Enzyme | 7.1E-15 | 0.377 | 0.923 |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
MMP8 | P22894 | matrix metallopeptidase 8 | Enzyme | 1.1E-24 | 0.488 | 0.808 |
KRT20 | P35900 | keratin 20 | 9.1E-11 | 0.388 | 0.846 | |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
IL4 | P05112 | interleukin 4 | 4.7E-03 | 0.332 | 0.962 | |
IL2 | P60568 | interleukin 2 | 0.48 | 0.336 | 0.885 | |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
IL17A | Q16552 | interleukin 17A | 4.3E-02 | 0.324 | 0.923 | |
IL10 | P22301 | interleukin 10 | 5.9E-03 | 0.281 | 0.923 | |
IFNG | P01579 | interferon gamma | 0.47 | 0.288 | 0.962 | |
HLA-DRB1 | P01911 | major histocompatibility complex, class II, DR beta 1 | Immune response | 1.1E-03 | 0.333 | 0.923 |